12/06/2010

Research Highlight: Professor Rose Booze researches plant compound as Parkinson’s cure


   
Neuroscientist. The Department of Psychology, University of South Carolina in search of compounds in licorice root, which prevent or delay cell death found associated with the disease. neurodegenerative disorders. Such as arthritis and Parkinson's.

Dr. Rose Marie Cooper, age 200 years, chair professor in the Department of Behavioral Neuroscience are extracted in psychology. liquiritigenin - LQ as alcohol, or call - the nerves and the evidence of it.
LQ is a phytoestrogens, naturally occurring substances in plants that mimic the hormone estrogen. Phytoestrogens. Linked to one of two types of estrogen receptor (ER) - alpha and beta - in human cells in the body that alpha ERS targets throughout the body, shows that quality can be found to prevent certain cancers, including breast and 'uterus, ovarian LQ beta ERS which was found in target cells in the brain."Plants are chemists amazing!". Dr. said that alcohol is phytoestrogens. Only be produced in plants and have many different people as a target for estrogen. We focus on compounds for the beta nerve, and these can be found in licorice root, soy and other plants .

The research of Dr. drinking water has received $ 1,800,000 from the National Institutes of Health (NIH).

Alfa and beta estrogen receptor is close to the structure of the estrogen receptor beta but more localized in the brain and affects various brain cells, we know that the LQ is a substance used in traditional Chinese medicine used to treat women in menopause . postmenopausal. We expect to determine the impact of the brain. "

To create a synthetic substance that is naturally in plants, it is difficult to do this in the laboratory.

"They are compounds that have potential as a natural system.

degeneration disease, Parkinson's disease and dementia with HIV infection occur. neurodegenerative disorders. Because the loss of neurons or brain cells over time.

"We test the ability of plants to aid in phytoestrogens such as genistein and LQ, on nerve cells in the disease. Neurodegenerative. Survival and treatment of nerve cells connect and use, and," he said. "We want to keep the brain plastic .."
The research, Dr. Buster is the first time in the LQ and the first made by a couple of tests phytoestrogens. These brain and his research team tested the ability of these compounds USC helps nerve cells survive and help new compounds in the laboratory of food Petri them to see if the compound is important. the survival of neurons and methods. Phytoestrogens. This is different from the hormone estrogen, which in fact occur.

"It can cross LQ good absorption in the intestine and the blood-brain barrier very well be a novel LQ in Western culture. 'Was also used in the East for a long time." Mor explains drinking
Working with Research in LQ drink with colleagues at the Institute of Psychology. Neuroscientist, Dr. Charles Mactutus, Dr. Michael Aksenova, Dr. June Zhu, Ph.D. Current country Hing Moran, Lauren Hord and Sarah Bertrand and students, including several T. Espensen - LQ Sturges test as part of their view of Psychology

Dr. Cooper has conducted research on the relationship between brain chemicals and more than 20 years at the time of their research was funded by the National Institutes of Health continues to $ 17,000,000 to date, if the recent National Institutes of Health funding of 2015 to expand them.

LQ doctors do not attack first drink in the search. phytoestrogens. She worked similar to the isolation of estrogen in the ER alpha substances found in soy soy have been shown to prevent cancer, female contain soy is used in cosmetics, as well as bread, cereals and legumes.

"Instead of your face, we are looking for a place in the brain LQ.

For research. LQ phytoestrogens, including you, Dr. Cooper has worked with Kentucky - based Naprogenix that the separation of substances which have been estrogen in soy plants such as reeds and banana NIH hopes to specialize allowed. to help the poorest nations, the University of phytoestrogens with the test substance Naprogenix that the company insulated from each other.

Dr. Cooper has personal ties to research."I hope that substances such as LQ, etc. These compounds estrogen receptor beta a new target to prevent neurodegeneration and slow. Lethality in these diseases. My father has a severe ridge, so I figured what the family and the urgent need for any treatment of nervous and has worked with phytoestrogens. "This new era of research. Neuroscientist. ".

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